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A collection of nonclinical studies & assays; customization is possible.

Immunohistochemistry (IHC)

Immunohistochemistry (IHC)

Immunohistochemistry (IHC) is a technique that utilizes antibodies that specifically recognize and bind different antigens in cells or tissue samples. The technique uses antibodies that are either conjugated to enzymes or a fluorescent dye to allow visualization of the distribution and localization of specific cellular components under a microscope.

The table below lists some examples of the cells which can be determined through CD markers via IHC across our facilities worldwide. 

Immune Cells (CD45*)

Species

NHP

Mouse

Rat

Porcine

Canine

Human

 

Lymphoid

T lymphocytes

CD3, CD4, CD8, CD16, CD278

CD3, CD4, CD8

CD3, CD8

CD3, CD8

CD3, CD4, CD8

CD3, CD4, CD8

B lymphocytes

CD19, CD20, CD21, CD79a, CD138

CD19, CD20, CD79a, CD45R

CD79a

CD79a

CD20

CD20

NK cells

CD8, CD16

CD8

CD8

CD8

CD8

CD8

Myeloid

(Macrophages, Dendritic cells, Mast cells, Granulocytes)

CD68, CD4, CD16, CD123, CD205, CD207, CD209, CD303

CD68, F4/80, CD4, CD117

CD68

 

CD4

CD68, CD66b, CD4

Read the blog post on the relationship between immunophenotyping & immunohistochemistry. [LINK COMING]

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